2-Mesitylenesulfonyl Chloride 2,4,6-三甲基苯磺酰氯

规格: 99%
CAS: 773-64-8
产品编号: H65188
MDL: MFCD00007434
品牌: INFI
Chemical Name2-Mesitylenesulfonyl chloride
Synonym 2-Mesitylenesulfonyl chloride {LY} 2-Mesitylenesulfonyl chloride {} {LY} 2-Mesitylenesulfonyl chloride {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {} {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Mesitylenesulfonyl chloride {} {} {} {} {} {} {} {} {}
CAS Number773-64-8
EC Number212-257-8
Beilstein Registry Number1107601
MDL NumberMFCD00007434
PubChem Substance ID87572184
Reaxys-RN1107601
Chemical Name Translation2,4,6-三甲基苯磺酰氯
Wiswesser Line NotationWSGR B1 D1 F1
InChIKeyPVJZBZSCGJAWNG-UHFFFAOYSA-N
LabNetwork Molecule IDLN00194080
InChIInChI=1S/C9H11ClO2S/c1-6-4-7(2)9(8(3)5-6)13(10,11)12/h4-5H,1-3H3
Canonical SMILESCC1=C(S(=O)(Cl)=O)C(C)=CC(C)=C1
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#02913

Signal word Danger
WGK Germany3
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
    Risk Statements
    • R29 Contact with water liberates toxic gas. 遇水释放出有毒气体
    • R34 Causes burns 会导致灼伤
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P234 Keep only in original container. 只保留在原来的容器中。
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P330+P331
      • P301+P330+P331+P310
      • P303+P361+P353+P310+P363
      • P304+P340+P310
      • P305+P351+P338
      • P305+P351+P338+P310
      • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
      • P390 Absorb spillage to prevent material damage. 吸收溢出物，防止重大损害。
      • P405 Store locked up. 上锁保管。
      • P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Hazard statements
        • H290 May be corrosive to metals 可能腐蚀金属。
        • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
          Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
          RTECSDB8930000
          Packing GroupII
          UN Number 3261 UN 3261 8/PG 2 UN3096
          Storage condition 2-8°C, sealed storage, away from moisture {LY} 2-8°C, sealed storage, away from moisture Moisture Sensitive Store at RT. Store at room temperature {} {LY} 2-8°C, sealed storage, away from moisture {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, awa
          Hazard Codes 8 C
          Hazard Class8
        • 多核苷酸合成中的偶联剂
        • {ALF} The indole nitrogen, e.g. in tryptophan residues, may also be protected as the Mts amide, stable to dilute alkali, hydrazine hydrate, TFA, 4N HCl in dioxane, or HBr in AcOH, but cleaved by MsOH, or TfOH in TFA: Chem. Pharm. Bull., 32, 2660 (1984). See Appendix 6.
        • {ALF} Reagent for protection of the guanidino function of arginine residues as mesitylenesulfonyl (Mts) derivatives in peptide synthesis: J. Chem. Soc., Chem. Commun., 482 (1978); Chem. Pharm. Bull., 26, 3752 (1978); Int. J. Pept. Prot. Res., 14, 169 (1979). Deprotection can be effected with triflic acid in TFA in the presence of thioanisole as a
        • {ALF} Selective reagent for sulfonylation of carbohydrates: J. Chem. Soc., Perkin 1, 1373 (1974).
        • {ALF} Reagent for protection of the guanidino function of arginine residues as mesitylenesulfonyl (Mts) derivatives in peptide synthesis: J. Chem. Soc., Chem. Commun., 482 (1978); Chem. Pharm. Bull., 26, 3752 (1978); Int. J. Pept. Prot. Res., 14, 169 (1979). Deprotection can be effected with triflic acid in TFA in the presence of thioanisole as a cation scavenger: J. Chem. Soc., Chem. Commun., 1063 (1980).
        • {ALF} For reviews of the use of hindered sulfonyl chlorides as condensing agents for the formation of the phosphate link of oligonucleotides, see: Angew. Chem. Int. Ed., 11, 451 (1972); Synthesis, 222 (1975); Chem. Rev., 77, 183 (1977). For reviews of oligonucleotide synthesis by the phosphotriester method, see: Heterocycles, 7, 1197 (1977); Tetrahedron, 34, 3143 (1978). Compare 2,4,6-Triisopropyl­benzenesulfonyl­ chloride, A11458.
        • {uni_hamburg} Short: III/20b
        • {uni_hamburg} Short: EINECS
          • 773-64-8

          化学属性

          Mol. FormulaC9H11ClO2S
          Mol. Weight218.70
          Density1.422
          Melting Point55-57°C
          Flash Point>110°(230°F)
          TSCANo
          Boiling Point303.1°C at 760 mmHg
          Solubility不溶
          Stability对湿度敏感

          *以上化合物性质及应用等信息仅供参考