2,4,6-Trichlorophenol 2,4,6-三氯苯酚

规格: 98%
CAS: 88-06-2
产品编号: H67334
MDL: MFCD00002172
品牌: INFI
Chemical Name2,4,6-Trichlorophenol
CAS Number88-06-2
PubChem Substance ID6914
EC Number201-795-9
Beilstein Registry Number6,190
MDL NumberMFCD00002172
Synonym 2,4,6-三氯苯酚;2,4,6-三氯酚 caswellno.880c 2,4,6 T 6-三氯苯酚 Dowcide 2S RCRA waste number U231 1,3,5-Trichloro-2-hydroxybenzene 2,4,6-三氯苯酚 2,4,6-三氯苯酚, 98% NCI-C02904 2,4,6-Trichlorfenol dowcide2s 2,4,6-三氯酚 DOWICIDE 2S ai3-00142 PHENACHLOR Dowicide 2S 2 2,4,6-trichloro-pheno 2,4,6-trichloro-2-hydroxybenzene epapesticidechemicalcode064212 2,4,6-三氯苯酚 DOWICIDE 2S(R) 2,4,6-三氯酚 056-01 [6] 2,4,6-trichlorfenol(czech) 1,3,5-Trichlorophenol 2,4,6-Trichlorophenol TRICHLOROPHENOL(2,4,6-) 2,4,6-TCP 2,4,6-三氯酚 4 OMAL 6-三氯酚 Phenachlor 2,4,6-TRICHLOROPHENOL
Reaxys-RN776729
Merck Number9644
Chemical Name Translation2,4,6-三氯酚
Wiswesser Line NotationQR BG DG FG
LabNetwork Molecule IDLN00193604
InChIInChI=1S/C6H3Cl3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 185 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - leukemia
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-155,1979

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 882 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-155,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 441 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-155,1979

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 374 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - leukemia
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/y

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C310,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 454 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 45(10),16,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 820 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,1176,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 276 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 13,20,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kil

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 30 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 280,175,1992

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 500 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   69,333,1989

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 100 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 303,101,1993

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 400 mg/L
REFERENCE :
   EVSRBT Environmental Science Research.  (Plenum Pub. Corp., 233 Spring St.,
   New York, NY 10013) V.1-    1972-  Volume(issue)/page/year: 12,325,1978

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 80 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   12,85,1988

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 400 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 303,101,1993

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TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 12500 mg/kg
SEX/DURATION            : female 2 week(s) pre-mating
                          female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   6,233,1986

WGK Germany3
Hazard statements
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H315 Causes skin irritation 会刺激皮肤
  • H351 Suspected of causing cancer 怀疑致癌
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
    Hazard Codes Xn,N,T,F
    Precautionary statements
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P308+P313
    • P332+P313
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
    • P301+P312+P330
    • P337+P313
    • P305+P351+P338
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
    • P305+P351+P338+P337+P313
    • P302+P352+P312+P361+P364
    • P405 Store locked up. 上锁保管。
    • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
      Signal word
      RTECSSN1575000
      UN Number UN 3077 9/PG 3 2020
      Safety Statements
      • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
      • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
      • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
      • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
        Risk Statements
        • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
        • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
        • R22 Harmful if swallowed 吞咽有害
        • R50/53
        • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
        • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
        • R11 Highly flammable 非常易燃
        • R52/53
          Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
          Packing GroupIII
          Storage condition 储存温度2-8℃ 0-6°C
          Hazard Class6.1
          Warnings 危险化学品
        • 农药、医药中间体
        • {ALD} Merck: 14,9644
        • Beilstein:6,190
        • {ALD} Merck: 14,9644
        • 88-06-2 H67334 2,4,6-Trichlorophenol	2,4,6-三氯苯酚

          化学属性

          Mol. FormulaC6H3Cl3O
          Mol. Weight197.44
          Boiling Point246 °C - lit.
          Melting Point 64 - 66 °C - lit.
          Density1.0
          Flash Point99°(210°F)
          TSCAYes
          Vapor Pressure1 mmHg ( 76.5 °C)
          Solubility0.8 g/L

          *以上化合物性质及应用等信息仅供参考