1-Methylimidazole 1-甲基咪唑

规格: 99%
CAS: 616-47-7
产品编号: H68153
MDL: MFCD00005292
品牌: INFI
Chemical NameN-Methylimidazole
Beilstein Registry Number105197
CAS Number616-47-7
PubChem Substance ID1390
EC Number210-484-7
MDL NumberMFCD00005292
Synonym 1-Methyl-1H-imidazole; Methyl imidazole; N-Methylimidazole N-Methylimidazole N-甲基咪唑 N-甲基咪唑,1-甲基-1H-咪唑 Imidazole, 1-methyl- 1-methyl-1h-imidazol 1-甲基-1H-咪唑 CAP B (1-METHYLIMIDAZOLE 10% IN N-METHYLIMIDAZOLE N-methyl glyoxaline 1-甲基咪唑 1H-Imidazole, 1-methyl- CAP B (1-METHYLIMIDAZOLE 12% IN ACETONIT 1-methyl-1h-imidazole 1-甲基咪唑(5KG禁止空运) 1-METHYLIMIDAZOLE, FOR DNA SYNTHESIS methyl imidazole CAP B (1-METHYLIMIDAZOLE 10% IN THF)* 1-甲咪唑 1-METHYLIMIDAZOLE 1-methylimidazole solution 1-Methylimidazole, >=99%, purified by redistillation 1-Methylimdazole 甲基引咪唑 {Chemicalbook
Chemical Name TranslationN-甲基咪唑
Reaxys-RN105197
Wiswesser Line NotationT5N CNJ A1
LabNetwork Molecule IDLN00195885
InChIInChI=1S/C4H6N2/c1-6-3-2-5-4-6/h2-4H,1H3
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 380 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   14,301,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   14,301,1969

WGK Germany1
Hazard Codes 8 C T,C,Xn Xn;C
Hazard statements
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
  • H302 Harmful if swallowed 吞食有害
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H312 Harmful in contact with skin 皮肤接触有害
  • H227 Combustible liquid 可燃液体
    Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSNI7000000
    Precautionary statements
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P301+P312+P330
    • P301+P330+P331
    • P303+P361+P353
    • P303+P361+P353+P310+P363
    • P304+P340
    • P304+P340+P310
    • P305+P351+P338
    • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      Safety Statements
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36 Wear suitable protective clothing 穿戴适当的防护服；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
        Risk Statements
        • R11 Highly flammable 非常易燃
        • R19 May form explosive peroxides 可能生成易爆的过氧化物质
        • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
        • R21 Harmful in contact with skin 与皮肤接触有害
        • R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
        • R22 Harmful if swallowed 吞咽有害
        • R24 Toxic in contact with skin 与皮肤接触有毒
        • R34 Causes burns 会导致灼伤
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
          Packing GroupII
          UN Number 1760 3267 UN2922
          Storage condition Store at RT. 密封保存 Hygroscopic
          Hazard Class8
        • 有机合成中间体和用作环氧树脂固化剂、粘合剂等；可广泛用于环氧树脂粘接、涂装、浇注、包封、浸渍及复合材料等。
        • {ALF} Reacts with acid chlorides, including chloroformates, to give N-acylimidazolium salts, which are useful reagents for the acylation of, for example, amino acids: Bull. Soc. Chim. Fr., 1021 (1973).
        • {ALF} Useful base for peptide coupling, etc. See, e.g.: J. Chem. Soc., Chem. Commun., 2223 (1995). For peptide reagents, see Appendix 6.
        • {ALF} Undergoes lithiation at the 2-position. Reaction of the Li derivative with ketones followed by dehydration with acetic anhydride is a good route to 2-alkylideneimidazoles: Synthesis, 78 (1990). Likewise, reaction with benzonitrile gives the 2-benzoyl derivative, the carbonyl group of which undergoes Wittig methylenation: Synth. Commun., 20, 321 (1990).
        • {ALD} Beilstein:23,46
          • 616-47-7 H68153 1-Methylimidazole 1-甲基咪唑

          化学属性

          Mol. FormulaC4H6N2
          Mol. Weight82.00
          Refractive index1.4920 to 1.4980
          Boiling Point198 °C(lit.)
          Density1.01
          Melting Point−63 - −57 °C(lit.)
          Autoignition Point977 °F
          Vapor Pressure0.4 mmHg ( 20 °C)
          Flash Point198 °F
          TSCAYes
          Appearance 外观：无色透明液体，熔点：-60℃，沸点：198℃， 密度d20/4=1.036g/ml。 含量：≥99% 。
          Stability易吸潮

          *以上化合物性质及应用等信息仅供参考