1,2-Dichlorobenzene 1,2-二氯苯

规格: 99%
CAS: 95-50-1
产品编号: H69296
MDL: MFCD00000535
品牌: INFI
Chemical Name1,2-Dichlorobenzene
CAS Number95-50-1
EC Number202-425-9
Beilstein Registry Number606078
MDL NumberMFCD00000535
Synonym Cloroben 2-二氯苯 1,2-Dichlorobenzene 1,2-二氯苯 AKOS BBS-00004357 Chloroben 1 o-DCB o-dichlorobenzene ODB 1,2-二氯代苯 1,2-Dichlorbenzene 1,2-DICHLOROBENZENE O-DICHLOROBENZENE Chloroden DCB Dichlorobenzene, o- 鄰-二氯苯 o-Dichlorobenzol Benzene, o-dichloro- 1,2-dichlorobenzene o-Dichlor benzol NCI-C54944 Dowtherm E 1,2-dichloro-benzene 1,2-二氯代苯, HPLC GRADE, 98% MIN Dilatin DB Benzene, o-dichloro- orthodichlorobenzene 1,2-二氯代苯, SPECTROPHOTOMETRIC GRADE Dilantin DB Benzene,o-dichloro- 1,2-二氯
PubChem Substance ID7239
Merck Number3056
Reaxys-RN606078
Chemical Name Translation1,2-二氯苯
Wiswesser Line NotationGR BG
LabNetwork Molecule IDLN00162943
InChIInChI=1S/C6H4Cl2/c7-5-3-1-2-4-6(5)8/h1-4H
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(i

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 840 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MEPAAX Medycyna Pracy.  Industrial Medicine.  (Ars-Polona, POB 1001, 00-068
   Warsaw 1, Poland) V.1-    1950-  Volume(issue)/page/year: 20,519,1969

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 821 ppm/7H
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Liver - hepatitis (hepatocellular necrosis), zonal
   Sense Organs and Special Senses (Eye) - lacrimation
REFERENCE :
   AMIHAB AMA Archives of Industrial Health.  (Chicago, IL)  V.11-21, 1955-60.
   For publisher information, see AEHLAU.  Volume(issue)/page/year: 17,180,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1228 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road,
   Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-  Volume(issue)/page/year: 2,111,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSU

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 187 mg/kg/24H
REFERENCE :
   MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road,
   Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-  Volume(issue)/page/year: 2,111,1987

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 59 mg/L
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   236,933,1987

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 6500 ug/L
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   236,933,1987

TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 250 mg/kg
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 4(2),224,1985

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 200 ppm/6H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   5,190,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 50 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 4(1),224,1985

Signal word Danger
WGK Germany2
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
    Risk Statements
    • R11 Highly flammable 非常易燃
    • R22 Harmful if swallowed 吞咽有害
    • R36 Irritating to eyes 刺激眼睛
    • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
    • R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
    • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
    • R51/53
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
    • R50/53
    • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
    • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
    • R52/53
    • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
      Precautionary statements
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P305+P351+P338
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P332+P313
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
      • P273 Avoid release to the environment. 避免释放到环境中。
      • P302+P350
      • P337+P313
      • P403+P233
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
      • P304+P340+P312
      • P333+P313
      • P201 Obtain special instructions before use. 使用前获取专门指示。
      • P302+P352+P333+P313+P362+P364
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P305+P351+P338+P337+P313
      • P308+P311
      • P303+P361+P353
        Hazard statements
        • H227 Combustible liquid 可燃液体
        • H315 Causes skin irritation 会刺激皮肤
        • H317 May cause an allergic skin reaction 可能导致皮肤过敏
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
        • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H302+H332
        • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
        • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
        • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
        • H302 Harmful if swallowed 吞食有害
          Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US)
          RTECSCZ4500000
          Packing GroupIII
          UN Number UN 1993 3/PG 2
          Hazard Codes Xn;N Xn,N,Xi,F,T F,Xn,N F,Xi,N Xn,N
          Storage condition 密封阴凉保存。 0-6°C
          Hazard Class6.1
          Warnings 危化品目录(2015)
        • 有机合成。溶剂。染料中间体。照明气中除硫。杀虫剂。热传递介质。金属去油。
        • Merck: 14,3056 Beilstein: 5,IV,654
        • Short: II/24B
        • Short: II/14a
        • Short: II/19b
        • Merck: 14,3056
        • 95-50-1 H69296 1,2-Dichlorobenzene
1,2-二氯苯

          化学属性

          Mol. FormulaC6H4Cl2
          Mol. Weight147.00
          Density1.306
          Refractive index1.5500 to 1.5530
          Autoignition Point1198 °F
          Vapor Density5.1 (vs air)
          Boiling Point178-180
          Vapor Pressure1.2 mmHg ( 20 °C)
          Melting Point-18 - -17
          Flash Point69°C(lit.)
          TSCAYes
          Solubility0.13 G/L (20 ºC)
          Stability对光敏感