Diethyl sulfate 硫酸二乙酯

规格: 98%
CAS: 64-67-5
产品编号: H76014
MDL: MFCD00009099
品牌: INFI
Chemical NameDiethyl sulfate
Synonym ETHYL SULFATE Diethylsulfate,98% 硫酸乙酯(硫酸二乙酯) 131-01 [6] 硫酸二乙酯 Diethylsulfat Ethylsulpate SULFURIC ACID DIETHYL ESTER sulfuric acid, diethyl ester DES DS diethyltetraoxosulfate DiethylSulphate99.5% sulfuric acid diethyl ester 二乙基硫酸 硫酸乙酯 DiethylSulfate,Certified diethylesterkyselinysirove Schwefelsäurediethylester DIETHYL SULFATE Diaethylsulfat ethyl sulfate Diethyl sulphate Sulfuric acid diethyl ester DIETHYL SULFATE (DRUMS) DIETHYL SULFATE (BULK) Sulphuric acid diethyl ester DiethylSulphateForSynthesis 硫酸乙酯 diethyl sulfate 硫酸二乙酯, 98% Diethylester kyseliny sirove SULPHONICACID,DIETHYLESTER DIETHYL SULPHATE Diethyl tetraoxosulfate Ethyl sulfate 二乙基硫酸 sulfatediethylique Diäthylsulfat diethylsulfate
MDL NumberMFCD00009099
CAS Number64-67-5
EC Number200-589-6
Merck Number3130
Beilstein Registry Number1,327
PubChem Substance ID6163
Reaxys-RN1209714
Chemical Name Translation硫酸二乙酯
Wiswesser Line Notation2OSWO2
LabNetwork Molecule IDLN00244624
InChIInChI=1S/C4H10O4S/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3700 mg/kg/81W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   74,241,1970

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 800 mg/kg/32W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   74,241,1970

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 85 mg/kg
                          female 15 day(s) after conception
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Reproductive - Tumorigenic effects - transplacental tumorigenesis
   Brain and Coverings - tumors
REFERENCE :
   IARCCD IARC Scientific Publications.  (Geneva, Switzerland)  No.1-26,
   1971-78.  For publisher information, see IAPUDO.  Volume(issue)/page/year:
   4,45,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   74,241,1970

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 250 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 31,343,1949

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 600 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 12/30/1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 880 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 31,60,1949

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Ro

TYPE OF TEST            : Micronucleu

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Rodent - mouse Ascites tumor
DOSE/DURATION           : 5 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 89,95,1981

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 9 gm/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 2,363,1981

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 300 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 205,409,1988

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 30 nmol/tube
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 79,5971,1982

TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 100 mg/kg/10W (Intermittent)
REFERENCE :
   GNKAA5 Genetika (Moscow).  For English translation, see SOGEBZ.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  No.1-    1965-
   Volume(issue)/page/year: 12(3),163,1976

TYPE OF TEST            : Sex chromosome loss and nondisjunction
RO

TYPE OF TEST            : Host-m

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 340 mg/kg
SEX/DURATION            : female 15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   IARCCD IARC Scientific Publications.  (Geneva, Switzerland)  No.1-26,
   1971-78.  For publisher information, see IAPUDO.  Volume(issue)/page/year:
   4,45,1973

RTECSWS7875000
Packing GroupII
UN Number 1594
Risk Statements
  • R46 May cause inheritable genetic damage 可能引起遗传基因损害
  • R45 May cause cancer 可能致癌
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R34 Causes burns 会导致灼伤
    Safety Statements
    • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
    • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
      WGK Germany3
      Hazard statements
      • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
      • H350 May cause cancer 可能致癌
      • H340 May cause genetic defects 可能导致遗传性缺陷
      • H302+H332
      • H311 Toxic in contact with skin 皮肤接触中毒
      • H332 Harmful if inhaled 吸入有害
      • H302 Harmful if swallowed 吞食有害
      • H312 Harmful in contact with skin 皮肤接触有害
      • H302+H312+H332
        Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
        Precautionary statements
        • P501 Dispose of contents/container to..… 处理内容物/容器.....
        • P305+P351+P338+P310
        • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
        • P303+P361+P353+P310+P363
        • P301+P330+P331+P310
        • P303+P361+P353
        • P201 Obtain special instructions before use. 使用前获取专门指示。
        • P305+P351+P338
        • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
          Signal word
          Hazard Codes T
          Hazard Class6.1
          Storage condition 干燥避光保存。 Refrigerator (+4°C)
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 有机合成。乙基化试剂。乙烯磺化作用的促进剂。
        • {ALF} Esterification of thermally unstable carboxylic acids, e.g. ß-keto acids, can be achieved in high yield in the presence of DBN (1,5-Diazabicyclo[4.3.0]non-5-ene, A13437): Synth. Commun., 6, 89 (1976).
        • {uni_hamburg} Short: II/27B
        • {ALD} Merck: 14,3130
        • {ALD} Merck: 14,3130
        • Beilstein:1,327
        • {uni_hamburg} Short: III/38B
        • {uni_hamburg} Short: II/5
        • 64-67-5 H76014 Diethyl sulfate	硫酸二乙酯

          化学属性

          Mol. FormulaC4H10O4S
          Mol. Weight154.18
          Density1.177
          Refractive index1.3990 to 1.4020
          Flash Point110°C(lit.)
          TSCAYes
          Boiling Point208°C(lit.)
          Melting Point-24 °C(lit.)
          Vapor Density5.3 (vs air)
          Vapor Pressure<;0.01 mmHg ( 20 °C)
          Solubility5 G/L (20 ºC)
          Stability对光敏感

          *以上化合物性质及应用等信息仅供参考