O-Methylhydroxylamine hydrochloride 甲氧基胺盐酸盐

规格: 99%
CAS: 593-56-6
产品编号: H86671
MDL: MFCD00012951
品牌: INFI
Chemical NameO-Methylhydroxylamine Hydrochloride
CAS Number593-56-6
Alfabeta NameMETHYLHYDROXYLAMINEHYDROCHLORIDE O-
MDL NumberMFCD00012951
Synonym Methoxyamine (hydrochloride) {LY} Methoxyamine (hydrochloride) {} {LY} Methoxyamine (hydrochloride) {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methoxyamine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID521874
Beilstein Registry Number3589723
EC Number209-798-7
Reaxys-RN3589723
Merck Number5989
Chemical Name Translation甲氧胺盐酸盐
Wiswesser Line NotationZO1 &GH
LabNetwork Molecule IDLN00008853
InChIInChI=1S/CH5NO.ClH/c1-3-2;/h2H2,1H3;1H
Canonical SMILESNOC.[H]Cl
GHS Symbol
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 900 mmol/L
REFERENCE :
   DKBSAS Doklady Biological Sciences (English Translation).  Translation of
   DANKAS: Biological Section. (Plenum Pub. Corp., 233 Spring St., New York, NY
   10013)  V.112-    1957-  Volume(issue)/page/year: 257,154,1981

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Cells - not otherwise specified
DOSE/DURATION           : 2 gm/L
REFERENCE :
   SOGEBZ Soviet Genetics.  English translation of GNKAA5.  (Plenum Pub. Corp.,
   233 Spring St., New York, NY 10013)  V.2-    1966- Volume(issue)/page/year:
   11,480,1975

TYPE OF TEST            : Specific locus test
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   2,331,1970

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 1 mol/L
REFERENCE :
   BBACAQ Biochimica et Biophysica Acta.  (Elsevier Science Pub. B.V., POB 211,
   1000 AE Amsterdam, Netherlands)  V.1-    1947- Volume(issue)/page/year:
   39

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURA

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Cells - not otherwise specified
DOSE/DURATION           : 2 gm/L
REFERENCE :
   SOGEBZ Soviet Genetics.  English translation of GNKAA5.  (Plenum Pub. Corp.,
   233 Spring St., New York, NY 10013)  V.2-    1966- Volume(issue)

Warnings HYGROSCOPIC, CORROSIVE
WGK Germany3
Hazard statements
  • H290 May be corrosive to metals 可能腐蚀金属。
  • H302 Harmful if swallowed 吞食有害
  • H302+H312
  • H312 Harmful in contact with skin 皮肤接触有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H318 Causes serious eye damage 严重伤害眼睛
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H351 Suspected of causing cancer 怀疑致癌
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
    Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    Hazard Codes 8 C,N C,Xi,N
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
    • P301+P312
    • P301+P330+P331
    • P302+P352
    • P303+P361+P353
    • P304+P340
    • P304+P340+P310
    • P305+P351+P338
    • P305+P351+P338+P310
    • P308+P313
    • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
    • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
    • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
    • P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
    • P330 Rinse mouth. 漱口
    • P332+P313
    • P333+P313
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
    • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
    • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      Safety Statements
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
        Risk Statements
        • R34 Causes burns 会导致灼伤
          RTECSNC3980000
          UN Number 3261
          Storage condition Store at room temperature, keep dry and cool {LY} Store at room temperature, keep dry and cool {} {LY} Store at room temperature, keep dry and cool {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {}
          Packing GroupII
          Hazard Class8
        • 是1,4-二烯-3-酮系统中保护酮基基团的试剂；用于依靠GLC2检测类固醇酮基基团的衍生试剂；靠GC3快速检测糖蛋白中的中性糖和氨基糖；用于酮的异构选择性还原反应 。
        • {ALF} As with oximes, the lithiation of methoximes results in abstraction of a proton syn to the oxygen function (coordination stabilization): J. Org. Chem., 41, 439 (1976). For a review of the alkylation of carbonyl compounds via their nitrogen-containing derivatives, see: Synthesis, 517 (1983).
        • {ALF} In the presence of KO-t-Bu and a copper catalyst in DMF, aminates nitroarenes at the ortho (predominantly) and para positions: J. Org. Chem., 61, 442 (1996).
        • {uni_hamburg} Short: III/20a
        • {ALF} Reacts with aldehydes and ketones to give O-methyloximes: J. Org. Chem., 27, 914 (1962); 28, 1523 (1963); Anal. Biochem., 22, 284 (1968). Open-chain aldoses have been prepared by ozonolysis of the methoximes of fully-acylated sugars: J. Org. Chem., 54, 4957 (1989).
        • {ALD} Merck:14,5989
        • Beilstein: 1,IV,1252
        • {uni_hamburg} Short: III/5a
        • {TRC} Herold, D.A
        • {ALD} Merck:14,5989
          • 593-56-6 H86671 O-Methylhydroxylamine hydrochloride 甲氧基胺盐酸盐

          化学属性

          Mol. FormulaCH6ClNO
          Mol. Weight83.52
          Refractive indexn20/D 1.4021
          Density1.1
          Melting Point151-154°C
          TSCAYes
          Solubility可溶
          Stability易吸潮
          Boiling Point105-110 °C at 760 mmHg

          *以上化合物性质及应用等信息仅供参考