α-Ketoglutaric acid α-酮戊二酸

规格: 98%
CAS: 328-50-7
产品编号: H93111
MDL: MFCD00004165
品牌: INFI
Chemical Name2-Oxoglutaric acid
CAS Number328-50-7
Alfabeta NameKETOGLUTARICACID 2-
MDL NumberMFCD00004165
Synonym 2-Ketoglutaric acid {LY} 2-Ketoglutaric acid {} {LY} 2-Ketoglutaric acid {} {} {LY} 2-Ketoglutaric acid {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Ketoglutaric acid {} {} {} {}
PubChem Substance ID87571945
EC Number206-330-3
Beilstein Registry Number3,789
Reaxys-RN1705689
Merck Number5303
Chemical Name Translation2-氧代戊二酸
InChIKeyKPGXRSRHYNQIFN-UHFFFAOYSA-N
LabNetwork Molecule IDLN00174890
InChIInChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
Canonical SMILESO=C(C(O)=O)CCC(O)=O
GHS Symbol
Warnings IRRITANT
WGK Germany3
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
    Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
    Hazard Codes Xi
    Precautionary statements
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P302+P350
    • P302+P352+P332+P313+P362+P364
    • P305+P351+P338
    • P305+P351+P338+P310
    • P305+P351+P338+P337+P313
    • P332+P313
    • P337+P313
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
      Signal word
      Safety Statements
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S39 Wear eye/face protection 戴眼睛/面孔保护装置；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
      • S37 Wear suitable gloves 戴适当手套；
        Risk Statements
          Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
          RTECSSA0454200
        • 色氨酸分析试剂，谷氨酸脱氢酶的底物(氨基转换酶及脱氢酶)。测定肝功能的配套试剂。
        • {MCE} [2]. Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec;105(Pt 3):1654-1662.
        • {ALD} Merck: 14,5303
        • {ALD} Merck: 14,5303
        • Beilstein:3,789
        • {MCE} [1]. Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79(4):419-35.
        • {MCE} [1]. Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79(4):419-35.
        • {MCE} [2]. Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec;105(Pt 3):1654-1662.
          • 328-50-7 H93111 α-Ketoglutaric acid α-酮戊二酸

          化学属性

          Mol. FormulaC5H6O5
          Mol. Weight146.10
          Melting Point113-115°C
          TSCAYes
          Density1.499
          Appearance alpha-酮戊二酸(328-50-7)为白色细结晶性粉末。熔点113.5℃。易溶于水、醇、极难溶于醚，久贮变淡灰黄色，易潮解。
          Boiling Point345.6°C at 760 mmHg

          *以上化合物性质及应用等信息仅供参考