Bromoform 三溴甲烷

规格: 99%
CAS: 75-25-2
产品编号: H97545
MDL: MFCD00000128
品牌: INFI
Chemical NameBromoform
Synonym Bromoform {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {ALD} {} {} {} {} {} {} {} {} {} {Chemicalbook} tribromomethane(bromoform) {} {} {} {} {} {} {} {} {} {} {Ch {} {} {} {} {} {} {} {} {} {} {Chemicalbook} tribromo-methan {} {} {} {} {} {} {} {} {} {} {} {Chemicalbook} tribromide {} {} {} {} {} {} {} {} {} {} {} {} {Chemicalbook} methyltribromide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {uni_hamburg} methane, tribromo- {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {uni_hamburg} bromoform {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {ALF} Tribromomethane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {uni_hamburg} Tribrommethan {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {hazard_com} Tribrommethaan {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {Chemicalbook} Rcra waste number U225 {} {} {} {} {} {} {} {} {} {}
CAS Number75-25-2
EC Number200-854-6
Beilstein Registry Number1731048
MDL NumberMFCD00000128
PubChem Substance ID5558
Merck Number1420
Reaxys-RN1731048
Chemical Name Translation三溴甲烷
Wiswesser Line NotationEYEE
LabNetwork Molecule IDLN00195512
InChIInChI=1S/CHBr3/c2-1(3)4/h1H
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1100 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   37,2717,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10400 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-350,1989

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1274 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 20(12),52,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1820 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,354,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 414 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - somnolence (general depressed activity)
   Behavioral - antipsychotic
REFERENCE :
   TOLED5 Toxicology Letters.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1977-  Volume(issue)/page/year: 15,251,1983

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 143 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals,"

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Multiple routes
TEST SYSTEM             : Non-mammalian species
DOSE/DURATION           : 5 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 292,83,1993

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 80 umol/L
REFERENCE :
   ENVRAL Environmental Research.  (Academic Press, Inc., 1 E. First St.,
   Duluth, MN 55802) V.1-    1967-  Volume(issue)/page/year: 32,72,1983

TYPE OF TEST            : Specific locus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 3000 ppm
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-350,1989

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 666 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 5(Suppl
   1),3,1983

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - rat Leukocyte
DOSE/DURATION           : 20 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 300,241,1993

{hazar

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 110 ug/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 7,1,1985

Signal word Danger
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S57 Use appropriate containment to avoid environmental contamination 使用适当容器避免环境污染;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S63
    Risk Statements
    • R11 Highly flammable 非常易燃
    • R22 Harmful if swallowed 吞咽有害
    • R23 Toxic by inhalation 吸入有毒
    • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
    • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
    • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
    • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
    • R51/53
      Precautionary statements
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P273 Avoid release to the environment. 避免释放到环境中。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P312+P330
      • P302+P350
      • P305+P351+P338
      • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
      • P332+P313
      • P337+P313
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Hazard statements
        • H302 Harmful if swallowed 吞食有害
        • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
        • H315 Causes skin irritation 会刺激皮肤
        • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
        • H331 Toxic if inhaled 吸入中毒
        • H319 Causes serious eye irritation 严重刺激眼睛
          Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          RTECSPB5600000
          Packing GroupIII
          UN Number 2515
          Storage condition 0-6°C 密封避光保存。 储存温度2-8℃ Light Sensitive 0-10°C 0-10
          Hazard Codes 6.1 T,N T,N,F
          Hazard Class6.1
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 测定分子量的溶剂,测定矿物的折射指数。按比重分离各种矿石。
        • 标准溶液用于水分析等以下用途。
        • 1、测定分子量的溶剂,测定矿物的折射指数。按比重分离各种矿石。
        • 2、工业上染料中间体、医药镇痛剂、空气熏蒸消毒剂、致冷剂、抗爆剂组分、树脂和石蜡的溶剂等。
        • 校准仪器和装置;评价方法;工作标准;质量保证/质量控制;其他。
        • 用于ICP-AES、AAS、AFS、ICP-MS、离子色谱等。滴定分析用标准溶液。
        • {ALF} For examples of the generation of dibromocarbene, using Potassium tert-butoxide, A13947, as base, see: Org. Synth. Coll., 6, 187 (1988); 7, 200 (1990). Alternatively, reactions can be carried out with aqueous OH- and a phase-transfer catalyst such as Benzyl­triethyl­ammonium chloride, A13268: Org. Synth. Coll., 8, 223 (1993), or using crown ether catalysis: Org. Synth., 75, 98 (1997).
        • {uni_hamburg} Short: II/27B
        • {ALF} Under phase-transfer conditions, allylic bromides undergo nucleophilic displacement by the tribromomethyl anion: J. Chem. Soc., Chem. Commun., 210 (1979).
        • {uni_hamburg} Short: II/25B
        • {SNA}
        • 75-25-2 H97545 Bromoform
三溴甲烷

          化学属性

          Mol. FormulaCHBr3
          Mol. Weight253
          Density2.87
          Refractive index1.5950 to 1.5990
          Vapor Density8.7 (vs air)
          Boiling Point150 °C
          Vapor Pressure5 mmHg ( 20 °C)
          Melting Point低熔点产品,冬季不易溶化
          Flash Point148 - 150 °C
          TSCAYes
          Solubility略溶于水, 0.301 G/100 ML
          Stability对光敏感
          pH:A

          *以上化合物性质及应用等信息仅供参考