Dibutyltin oxide 二丁基氧化锡

CAS: 818-08-6
产品编号: HXYJ0000002854
MDL: MFCD00001992
品牌: Bellen
Chemical NameDi-n-butyltin oxide, 98%
MDL NumberMFCD00001992
Synonym dbot Dibutyloxotin 二正丁基氧化锡 dibutylstanniumoxide Stannane,dibutyloxo- DIBUTYLTIN OXIDE 二正丁基锡氧化物 dibutyloxideoftin DIBUTYLTIN(IV) OXIDE kyslicnikdi-n-butylcinicity di-n-dibutyltinoxide Di-n-butyltin oxide Dibutyloxide of tin Dibutyloxostannane 氧化二丁基锡 DBOT 氯化二丁基锡 dibutyloxo-ti DIBUTYLOXOSTANNANE Tin, dibutyl-, oxide dbto Dibutyltin oxide dibutyloxo-stannan Dibutylstannium oxide di-n-butyl-zinn-oxyd di-n-dibutyltin 二丁基氧化锡 di-n-butylslannicoxide dibutyltinmonoxide 二丁錫氧 Dibutylstannane oxide DI-N-BUTYLTIN OXIDE dibutylstannaneoxide Di-n-butyl-zinn-oxyd dibutyl-tioxide Tin, dibutyloxo- 二丁基氧化錫 DIBUTYLOXOTIN Kyslicnik di-n-butylcinicity
EC Number212-449-1
CAS Number818-08-6
Beilstein Registry Number4126243
PubChem Substance ID24851031
Chemical Name Translation二丁基氧化锡
Wiswesser Line NotationO-SN-4&4
LabNetwork Molecule IDLN01268854
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 40 mg/kg
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - general anesthetic
   Behavioral - somnolence (general depressed activity)
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 7,47,1969

TYPE OF TEST            : LDLo - Lowest published lethal dose
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1500 mg/kg
   Details of toxic effects not reported other than lethal dose value
   SAIGBL Sangyo Igaku.  Japanese Journal of Industrial Health.  (Nippon Sangyo
   Eisei Igakkai, Kosu Eisei Bldg., 1-29-8, Shinjuku, Shinjuku-ku, Tokyo 160,
   Japan)  V.1-    1959-  Volume(issue)/page/year: 15,3,1973

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >2 gm/kg
   Lungs, Thorax, or Respiration - other changes
   Kidney, Ureter, Bladder - other changes
   Skin and Appendages - dermatitis, other (after systemic exposure)
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0570737

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 44900 ug/kg
   Details of toxic effects not reported other than lethal dose value
   85JCAE "Prehled Prumyslove Toxikologie;

TYPE OF TEST            : TDLo - Lowest published toxic dose
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 19916 ug/kg
SEX/DURATION            : female 8 day(s) after conception
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 85,149,1993

Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S39 Wear eye/face protection 戴眼睛/面孔保护装置;
  • S29 Do not empty into drains 不要排入下水道;
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
    Packing GroupII
    UN Number 3146 UN 3146 6.1/PG 2 UN3146
    Risk Statements
    • R25 Toxic if swallowed 吞咽有毒
    • R38 Irritating to skin 刺激皮肤
    • R48/25
    • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
    • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
    • R60 May impair fertility 可能降低生殖能力
    • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
    • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
    • R50/53
    • R51/53
    • R36 Irritating to eyes 刺激眼睛
      Precautionary statements
      • P273 Avoid release to the environment. 避免释放到环境中。
      • P301+P310
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P305+P351+P338
      • P201 Obtain special instructions before use. 使用前获取专门指示。
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
        Hazard statements
        • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
        • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
        • H318 Causes serious eye damage 严重伤害眼睛
        • H300 Fatal if swallowed 吞食致命
          WGK Germany3
          Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
          Signal word Danger
          Hazard Codes T,N T
          Hazard Class6.1
          Restrict 剧毒化学品
          Warnings 危化品目录(2015)
        • {ALF} Reacts with 1,2-diols to form 5-membered cyclic dibutylstannoxane derivatives. For use in the glycoside field, see: Synthesis, 409 (1995). Formation of these derivatives is greatly accelerated by microwave irradiation: Synlett, 89 (1994). The stannylene derivatives are activated to electrophilic attack:
        • {ALF} With bromine, the ɑ-hydroxy ketone is formed: J. Chem. Soc., Perkin 1, 1568 (1979). With acyl or sulfonyl chlorides, overall regioselective monoacylation of the diol at the more substituted hydroxyl can be achieved: Tetrahedron Lett., 21, 221 (1980); J. Chem. Soc., Chem. Commun., 1457 (1985); J. Org. Chem., 55, 5132 (1990); 61, 5257 (1996). Selective monotosylation of 1,2-diols has also been achieved catalytically: Tetrahedron Lett., 41, 3773 (2000).
        • {ALF} Catalyst for lactonization and lactamization reactions: J. Am. Chem. Soc., 102, 7578 (1980), particularly useful in the formation of macrolides: J. Am. Chem. Soc., 105, 7130 (1983). For catalysis of N-acylation of hydroxy alcohols with microwave irradiation, see: J. Org. Chem., 61, 5264 (1996).
        • {ALF} Promotes the cycloaddition of Trimethyl­silyl­ azide, L00173 to nitriles to give 5-aryltetrazoles, some of which are important as angiotensin II inhibitors: J. Org. Chem., 58, 4139 (1993):
        • {ALF}
        • {ALF} Catalyst for the dehydration of amides to nitriles under neutral conditions: Synthesis, 1724 (1999); for use of microwave irradiation, see: J. Org. Chem., 64, 1713 (1999).
        • {ALF} For a brief feature on uses of the reagent in synthesis, see: Synlett, 1847 (2004).
        • 818-08-6 HXYJ0000002854 Dibutyltin oxide	二丁基氧化锡


          Mol. Formula(CH3CH2CH2CH2)2SnO
          Mol. Weight248.94
          Melting Point>=300 °C(lit.)
          Autoignition Point534 °F
          Solubility4.0 MG/L (20 ºC)
          Flash Point81-83°C
          Boiling Point>300°C
          Density1,5 g/cm3