研峰科技 Infinity Scientific

二苯并-18-冠醚-6

规格:

CAS: 14187-32-7

产品编号: HXYJ0000015137

MDL: MFCD00005098

品牌: Bellen

Chemical Name	Dibenzo-18-Crown-6
Synonym	1,4,7,14,17,20-Hexaoxa[7.7]orthocyclophan 2,3,11,12-Dibenzo-1,4,7,10,13,16-hexaoxacyclooctadeca-2,11-diene 2,3,11,12-Dibenzo-1,4,7,10,13,16-hexaoxacyclooctadeca-2,11-diene; 6,7,9,10,17,18,20,21-Octahydrodibenzo[b,k][1,4,7,10,13,16]hexaoxacyclooctadecene 2,3,11,12-二苯并-1,4,7, 2,3,11,12-二苯并-1,4,7,10,13,16-六氧杂环十八-2,11-二烯 6,7,9,10,17,18,20,21 2,3-11,12-Dibenzo-1,4,7,10,13,16-hexaoxacyclooctadeca-2,11-d 6,7,9,10,17,18,20,21-Octahydrodibenzo(b,k)(1,4,7,10,13,16)hexaoxacyclooctadecin 6,7,9,10,17,18,20,21-octahydro-5,8,11,16,19,22-hexaoxa-dibenzo(a,j)cylooctadecene Dibenzo-18-crown-6-ether Dibenzo-18-krone-6 Dibenzocrown dibenzo-18-crovn-6 dibenzo-18-crown-6 dibenzo-18-crown-6 ether dibenzo[a,j]-1,4,7,10,13,16-hexaoxacyclooctadeca-2,11-diene 二苯并-18-冠醚-6
MDL Number	MFCD00005098
EC Number	238-041-3
CAS Number	14187-32-7
Merck Number	2602
Beilstein Registry Number	1162153
PubChem Substance ID	87568020
Reaxys-RN	1162153
Chemical Name Translation	二苯并-18-冠醚-6

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 430 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 31(2),48,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4500 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(11),72,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 430 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 31(2),48,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 560 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095

RTECS	HP5386000
Safety Statements
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
R36 Irritating to eyes 刺激眼睛
WGK Germany	2
Precautionary statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P305+P351+P338 P305+P351+P338+P337+P313 P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。 P332+P313 P337+P313
Hazard statements
H319 Causes serious eye irritation 严重刺激眼睛 H303 May be harmfully swallowed 吞食可能有害
Signal word	Warning
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xi

{uni_hamburg} Short: LC

{ALF} Catalyst for the halogenative cleavage of epoxides with Br2 or I2, giving halohydrins in high yields: J. Org. Chem., 63, 1455 (1998).

{ALF} In combination with Benzyltriethylammonium chloride, A13268, promotes the oxidative decarboxylation of arylacetic acids with NaIO4 to give high yields of the aryl aldehydes: Indian J. Chem. B, 35B, 151 (1996). Under the same conditions, phenacyl bromides are converted to benzoic acids.

{ALF} Catalyst for the formation of phenacyl esters from phenacyl bromides and K salts of carboxylic acids in acetonitrile: Synth. Commun., 26, 1747 (1996).

{ALF} Comparison of the rates of displacement of F- in 1-fluoro-2- or 4-nitrobenzene with KOMe and KO-t-Bu in the presence of this crown ether gave a result (t-BuO- >;>; MeO-) opposite to the pattern observed in its absence: J. Chem. Soc., Perkin 2, 55 (1973).

{ALF} Catalyst for the halogenative cleavage of epoxides with Br2 or I2, giving halohydrins in high yields: J. Org. C

{uni_hamburg} Short: EINECS

{ALF} See also 18-Crown-6, A11249 and Appendix 2.

{ALF} Promotes the generation of bromochlorocarbene from Chlorodibromomethane, A16938: Syntheis, 783 (1977); Tetrahedron, 33, 363 (1977), and of dibromocarbene from Bromoform, A11904: Org. Synth., 75, 98 (1997).

{uni_hamburg} Short: IV/8A

化学属性

Mol. Formula	C20
Mol. Weight	360
Melting Point	162-164
TSCA	Yes
Boiling Point	382°C(lit.)
Density	1.108
Solubility	微溶

*以上化合物性质及应用等信息仅供参考