Chemical Name | 4-Bromofluorobenzene |
CAS Number | 460-00-4 |
Alfabeta Name | BROMOFLUOROBENZENE 14--- |
MDL Number | MFCD00000342 |
PubChem Substance ID | 9993 |
EC Number | 207-300-2 |
Beilstein Registry Number | 774102 |
Reaxys-RN | 774102 |
Synonym |
1-Bromo-4-fluorobenzene
1-Bromo-4-fluorobenzene; p-Bromofluorobenzene
1-Fluoro-4-bromobenzene
1-bromo-4-fluoro-benzen
1-氟-4-溴苯
1-溴-4-氟苯
4-Bromo-1-fluorobenzene
4-Bromofluorobenzene
4-FLUOROBROMOBENZENE
4-Fluorobromobenzene
4-Fluorophenyl bromide
4-bromofluorobenzene
4-fluorophenylbromide
p-Fluorbrombenzol
Benzene, 1-bromo-4-fluoro-
Benzene,1-bromo-4-fluoro-
P-BROMOFLUOROBENZENE
nsc10268
p-fluorophenylbromide
对氟溴苯;4-溴氟苯;1-溴-4-氟苯 |
Chemical Name Translation | 对氟溴苯 |
InChIKey | AITNMTXHTIIIBB-UHFFFAOYSA-N |
LabNetwork Molecule ID | LN00176996 |
InChI | InChI=1S/C6H4BrF/c7-5-1-3-6(8)4-2-5/h1-4H |
Warnings |
IRRITANT |
GHS Symbol
WGK Germany | 3 |
Hazard statements | |
- H226 Flammable liquid and vapour 易燃液体和蒸气
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
- H332 Harmful if inhaled 吸入有害
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
|
Personal Protective Equipment |
Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
Hazard Codes |
3
Xn |
RTECS | CY9033750 |
Precautionary statements | |
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P233 Keep container tightly closed. ?保持容器密闭。
- P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
- P241+P242+P243
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P303+P361+P353
- P305+P351+P338
- P305+P351+P338+P337+P313
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P332+P313
- P337+P313
- P403+P235
- P501 Dispose of contents/container to..… 处理内容物/容器.....
|
Signal word |
Warning |
Safety Statements | |
- S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S7 Keep container tightly closed 保存在严格密闭容器中;
|
Risk Statements | |
- R10 Flammable 易燃
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
|
Storage condition |
<;0
<0°C
储存温度2-8℃
0-6°C |
UN Number |
1993 |
Packing Group | III |
Hazard Class | 3 |
有机合成中间体。
{uni_hamburg} Short: III/20b
{uni_hamburg} Short: III/31b
{ALFA} The Br undergoes selective displacement with Na alkoxides in NMP, in the presence of CuBr: Tetrahedron, 48, 3633 (1992).
{ALFA} Lithiation with LDA at -75o results mainly in deprotonation ortho to F; subsequent reaction with CO2 gives 5-bromo-2-fluorobenzoic acid: Tetrahedron Lett., 33, 7495 (1992). Improved yields are obtained by the use of Li 2,2,6,6-tetramethylpiperidide (LTMP) as base: Tetrahedron Lett., 37, 6551 (1996).
{ALD} Beilstein: 5,IV,678